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Traditional thinking is that compact spectrometers do not offer the sensitivity or speed needed to compete with benchtop fluorimeters for many fluorescence measurements. We explain how limit of detection (LOD) and limit of quantitation (LOQ) are defined and measured, and challenge that preconception by demonstrating picomolar LOD for fluorescein with a compact, cost-effective spectrometer capable of capturing 50 ms scans with ease.
Measuring optical signals in the femtowatt (10-15) to nanowatt (10-9) range can be a daunting task. In order to achieve significant improvements in noise rejection we need to turn to a lock-in amplifier, which can improve noise rejection by 3 orders of magnitude or more.
ProPhotonix, a high technology designer and manufacturer of LED illumination systems and laser diode modules, with operations in Ireland and the United Kingdom, is pleased to announce a new partnership with Integrated Optics
OSI Optoelectronics (OSIO), a supplier of standard and OEM photodiodes and high-power light sources, now offers UV-enhanced planar diffused silicon photodiodes specially designed for low-light-level detection in the ultraviolet spectral range