fluorescence

How multi-line lasers simplify and help commercialise biomedical imaging systems

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Multi-line lasers are an attractive alternative to laser combiners to simplify fluorescence-based imaging instrumentation. Furthermore, they help commercialise new, cutting-edge imaging systems for clinical use. This white paper explores the advantages of a permanently aligned multi-line laser, giving examples of how such a laser is used in microscopes developed at Julius-Maximilian-University of Würzburg and the University of Washington.

Challenging the Limit of Detection of Compact Spectrometers

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Traditional thinking is that compact spectrometers do not offer the sensitivity or speed needed to compete with benchtop fluorimeters for many fluorescence measurements. We explain how limit of detection (LOD) and limit of quantitation (LOQ) are defined and measured, and challenge that preconception by demonstrating picomolar LOD for fluorescein with a compact, cost-effective spectrometer capable of capturing 50 ms scans with ease.

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