Luxendo, a Bruker company, has extended its InVi SPIM microscope to include full incubation capabilities, as well as flexible illumination and detection optics. Luxendo’s single-plane illumination microscopy (SPIM) technique reduces sampling times over conventional laser scanning confocal microscopes, while reducing phototoxicity and damaging side effects on living specimens. The new technology also enables the fastest scan speeds for volumetric imaging of small organisms, cell monolayers, and cleared tissue.